Final answer:
Toxin A and Toxin B of Clostridium difficile lead to diarrhea and damage to the colon by inactivating small GTP-binding proteins, causing cell death and inflammation. This results in symptoms such as watery diarrhea, abdominal pain, and fever.
Step-by-step explanation:
The toxins TcdA and TcdB produced by Clostridium difficile lead to diarrhea and damage in the colon. These toxins inactivate small GTP-binding proteins, causing actin condensation, cell rounding, and cell death. Ultimately, this results in inflammation of the colon, the development of a pseudomembrane, and symptoms such as watery diarrhea, abdominal pain, and fever. If left untreated, it can lead to more severe complications like colon perforation and septicemia.