Final answer:
The nurse should respond by offering information about Alcoholics Anonymous, providing an empathetic and resourceful approach without judgment to the client who has been drinking excessively.
Step-by-step explanation:
The most appropriate response for a nurse to make to a client who has been drinking a lot since the loss of a friend is to provide empathetic support and resources that could help them address their drinking behavior. A response like 'Can I give you some information about Alcoholics Anonymous?' would be fitting as it offers a supportive resource without judgment or confrontation. This approach aligns with the understanding that alcohol abuse may stem from situational stressors and that treating individuals with compassion can lead to better outcomes.