Final answer:
The CREST acronym in systemic sclerosis stands for Calcinosis, Raynaud's phenomenon, Esophageal dysfunction, Sclerodactyly, and Telangiectasia, which are the main features of this condition.
Step-by-step explanation:
The acronym CREST represents a variant of systemic sclerosis (also known as scleroderma) and stands for:
- Calcinosis - the formation of calcium deposits in the skin
- Raynaud's phenomenon - episodes of decreased blood flow to the fingers and toes
- Esophageal dysfunction - problems with swallowing due to effects on the esophagus
- Sclerodactyly - thickening and tightening of the skin on the fingers and toes
- Telangiectasia - small red spots on the skin caused by dilation of capillaries