Final answer:
Systemic glucocorticoid medications are used as the last choice for the treatment of rheumatoid arthritis due to their many side effects.
Step-by-step explanation:
Glucocorticoid medications are used as the last choice for the treatment of rheumatoid arthritis primarily because they have many side effects.
Glucocorticoids are steroids that can suppress the immune system and reduce inflammation in the body. While they can be effective in managing the symptoms of rheumatoid arthritis, they are associated with significant side effects when used for long periods of time.
These side effects can include weight gain, high blood pressure, increased risk of infections, and osteoporosis.