Final answer:
COPII-coated vesicles transport materials from the endoplasmic reticulum to the Golgi apparatus, where they fuse with the cis face for further processing.
Step-by-step explanation:
COPII-coated vesicles are involved in the transport of materials from the endoplasmic reticulum (ER) to the Golgi apparatus. These vesicles are responsible for carrying proteins and lipids that have been synthesized in the ER to the cis face of the Golgi apparatus for further modification, sorting, and tagging. The transition vesicles that bud off from the ER with the help of COPII coat proteins eventually fuse with the cis Golgi vesicles, where they are further processed through the Golgi stack.
Once processed, additional transport vesicles containing the modified proteins and lipids pinch off from the Golgi apparatus on its outgoing, or trans face, and move to fuse with the plasma membrane or other organelles. Thus, COPII-coated vesicles are not directly involved in the transport between the Golgi apparatus and the plasma membrane or between endosomes and lysosomes.