Final answer:
The effective population size with 50 males and 100 females, under the assumptions of random mating and no selection, mutation, or migration, is 133, corresponding to option 2).
Step-by-step explanation:
The effective population size, also known as Ne, can be calculated using the following formula: Ne = (4 * Nm * Nf) / (Nm + Nf), where Nm is the number of males and Nf is the number of females in the population.
In this case, with 50 males and 100 females, the formula becomes Ne = (4 * 50 * 100) / (50 + 100), which simplifies to Ne = (20000) / (150), resulting in Ne = 133.33, which we round to the nearest whole number.
This calculation assumes random mating, no selection, mutation, or migration, conditions which are often outlined in Hardy-Weinberg principles. Hence, the effective population size would be 133, which aligns with option 2).
In this case, Nm = 50 and Nf = 100. Plugging these values into the formula, we get Ne = (4 * 50 * 100) / (50 + 100) = 133.33.
Rounding to the nearest whole number, the effective population size is 133.