Final answer:
Clinical manifestations of withdrawal in a newborn of a known opioid user may include tremors, poor feeding, diarrhea, excessive sleepiness, and sneezing.
Step-by-step explanation:
When assessing a newborn of a known opioid user for signs of withdrawal, the nurse can expect to identify several clinical manifestations. These may include tremors, which are involuntary shaking movements; poor feeding, as the infant may have difficulty latching or maintaining a steady suck; diarrhea, which can be a result of gastrointestinal upset; excessive sleepiness, as opioids can cause drowsiness; and sneezing, which can be a sign of nasal congestion or irritation. It's important for the nurse to closely monitor the newborn for these signs and provide appropriate care and treatment.