Question

A 33-year-old G2P1 woman at 29 weeks gestation presents with confirmed preterm premature rupture of membranes. She denies labor. She takes prenatal vitamins and iron. She denies substance abuse, smoking or alcohol use. Her prior pregnancy was delivered vaginally at 41 weeks after spontaneous rupture of membranes. Her blood pressure is 110/70; pulse 84; temperature 98.6°F (37.0°C). Which of the following is the best medication to delay the onset of labor?

1) Antibiotics
2) Betamethasone
3) Calcium channel blocker
4) Beta mimetics
5) Magnesium sulfate

Answer 1

The best medication to delay the onset of labor in a woman with PPROM at 29 weeks gestation is a beta mimetic, as they are specifically designed to relax the uterus and prevent contractions.

Step-by-step explanation:

A 33-year-old G2P1 woman at 29 weeks gestation presents with confirmed preterm premature rupture of membranes (PPROM). She denies labor and her vital signs are stable. The best medication to delay the onset of labor in this scenario is a beta mimetic, as their primary use is to relax the uterus and prevent contractions, thereby delaying labor. Magnesium sulfate may also be used for fetal neuroprotection and to delay labor, but is not as effective as beta mimetics for inhibiting labor. Antibiotics may be used to prevent infection, Betamethasone is administered to promote fetal lung maturity, and Calcium channel blockers can be used to relax the uterus, but beta mimetics are the preferred agents for tocolysis (labor inhibition) in the context of PPROM without labor.

Answer 2

The best medication to delay the onset of labor in preterm premature rupture of membranes (PPROM) is antibiotics. The correct option is 1.

Step-by-step explanation:

The best medication to delay the onset of labor in a case of preterm premature rupture of membranes (PPROM) is antibiotics. Antibiotics are given to prevent infection, which is a common complication when the amniotic sac has ruptured. Infection can lead to preterm labor and delivery.

Other medications like betamethasone, calcium channel blockers, beta mimetics, and magnesium sulfate may have other uses in the management of preterm labor, but in the case of PPROM, antibiotics are the most appropriate choice to delay labor. Hence, 1 is the correct option.