Question

An amplification of a signal could occur when cAMP activates protein kinase A?

1) True
2) False

Answer 1

Amplification of a signal occurs when cAMP activates Protein Kinase A, leading to a cascade of phosphorylation and activation of other enzymes, which amplifies the initial signal. option 1 is the correct answer.

Step-by-step explanation:

The amplification of a signal indeed could occur when cyclic AMP (cAMP) activates Protein Kinase A (PKA). This process begins when an effector molecule such as a hormone binds to a receptor, leading to the activation of a G-protein.

The G-protein in turn activates adenylyl cyclase, which converts ATP into cAMP. The cAMP then binds to inactive PKA, inducing a conformational change that results in the dissociation and activation of PKA. Active PKA can then phosphorylate various target proteins, essentially acting as a signal amplifier within the cell.

Thus, the answer to the question "An amplification of a signal could occur when cAMP activates Protein Kinase A?" is True (1), as cAMP binds to and activates Protein Kinase A, which in turn can phosphorylate and activate many other enzymes in a signaling cascade, amplifying the initial signal.