Question

Jaundice occurring with 48 to 72 hours of birth, physiologic jaundice, is a consequence of

a) Liver dysfunction
b) Excessive red blood cell breakdown
c) Immature liver function
d) Bacterial infection

Answer 1

Physiologic jaundice in newborns is principally caused by immature liver function and is characterized by high levels of bilirubin in the blood. This type of jaundice is common and can be treated with phototherapy to prevent complications.

Step-by-step explanation:

Physiologic jaundice, which occurs within 48 to 72 hours of birth, is generally a result of immature liver function. Although the newborn's liver is structurally complete, its enzymatic pathways are not fully mature at birth, leading to a slower processing of bilirubin. Bilirubin, a product of the normal breakdown of red blood cells, is processed by the liver and secreted in bile. Excessive bilirubin in the blood gives rise to jaundice, characterized by the yellowing of the skin and mucous membranes. Hyperbilirubinemia, or a high level of bilirubin in the circulation, is commonly treated with phototherapy to prevent potential neurotoxicity and brain damage in newborns.