Question

Calculate the correct Net Filtration Pressure in mmHg if arterial pressure is 55, the efferent arteriole pressure is 10, the afferent arteriole pressure is 50, the glomerular hydrostatic pressure is 40, the capsular hydrostatic pressure is 5, and the blood colloid osmotic pressure is 10?

Answer 1

The Net Filtration Pressure (NFP) can be calculated with the glomerular blood hydrostatic pressure, capsular hydrostatic pressure, and blood colloid osmotic pressure; the NFP with given values is 25 mmHg.

Step-by-step explanation:

To calculate the Net Filtration Pressure (NFP) in the glomerulus, we would use the following formula: NFP = Glomerular blood hydrostatic pressure (GBHP) - [capsular hydrostatic pressure (CHP) + blood colloid osmotic pressure (BCOP)]. Given the values, the GBHP is 40 mmHg (not the arterial pressure of 55 mmHg, as this is not what directly contributes to the NFP), the CHP is 5 mmHg, and the BCOP is 10 mmHg.

Substitute these numbers into the formula to get the NFP:

NFP = 40 mmHg - (5 mmHg + 10 mmHg) = 25 mmHg. This is the pressure that drives filtration in the kidneys.

It should be noted that while a typo in the question mentioned efferent arteriole pressure and afferent arteriole pressure, these are not directly used in the provided formula. This question also emphasizes the importance of maintaining adequate blood pressure to sustain kidney function and avoid conditions like shock due to impaired renal function.