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What term best describes the action of TNF-μ on eosinophils?

1) Antagonistic
2) Cascade inducible
3) Pleiotropic
4) Redundant
5) Synergistic

1 Answer

2 votes

Final answer:

The action of TNF-α on eosinophils is best described as pleiotropic, addressing its multiple effects and central role in inflammatory responses.

Step-by-step explanation:

Pleiotropy refers to a single gene or protein having multiple effects or actions in different tissues or cell types. TNF-μ, also known as tumor necrosis factor-μ, is a cytokine that can have diverse functions depending on the context. In the case of eosinophils, TNF-μ can regulate their recruitment, activation, and release of granule contents to combat parasites and contribute to allergic responses.

The term that best describes the action of TNF-α (tumor necrosis factor-alpha) on eosinophils is pleiotropic. TNF-α is a pro-inflammatory cytokine and a critical component of the inflammatory response. It has multiple effects on different cell types, including eosinophils. Pleiotropy refers to the ability of a single gene or molecule to have multiple effects on different physiological or cellular processes. In the context of eosinophils, TNF-α could modulate their activity, survival, and recruitment during inflammation. Considering eosinophils' involvement in allergic responses and parasitic infections, TNF-α's diverse actions appropriately exemplify pleiotropic effects.

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