Final answer:
The first step in preparing for a sterile procedure is hand hygiene with an alcohol-based hand rub, as it is critical for maintaining asepsis and preventing contamination.
Step-by-step explanation:
The first action a nurse should perform when preparing for a sterile procedure is C.) Perform hand hygiene with alcohol-based hand rub. This initial step is crucial in the process of maintaining aseptic technique. Proper hand hygiene is the most effective method to prevent the transmission of pathogens and to ensure the safety of the procedure. After cleaning the hands thoroughly, the nurse may proceed with subsequent steps such as donning personal protective equipment, placing necessary supplies in the room, and identifying the client.
Furthermore, strict aseptic techniques need to be followed throughout the procedure to maintain a sterile field and to avoid any contamination that might lead to sepsis. This includes using pre-sterilized equipment and proper protocols for handling specimens and equipment, thus minimizing the risk of infection.