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Which of the following statements about metformin is untrue?

a. Metformin works by decreasing hepatic glucose production and increasing peripheral cell sensitivity to insulin.

b. Metformin can cause lactic acidosis.

c. Metformin is typically used in conjunction with other diabetes medications.

d. Metformin cannot be used in patients with significant renal impairment.

1 Answer

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Final answer:

The untrue statement about metformin is that it cannot be used in patients with significant renal impairment.

Step-by-step explanation:

The untrue statement about metformin is d. Metformin cannot be used in patients with significant renal impairment. Metformin is a medication commonly used to treat type 2 diabetes. It works by decreasing hepatic glucose production and increasing peripheral cell sensitivity to insulin, which helps lower blood glucose levels. Metformin can cause lactic acidosis, but it can be used in patients with renal impairment, although the dosage may need to be adjusted based on their kidney function.

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