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What type of tubular dysfunction is seen with the following:

-Can be caused by toxic and/or hypoxic insult
-Decreased excretion/reabsorption ability
-Not responsive to ADH and aldosterone
-Water and electrolyte imbalance
-Acidosis and glycosuria
a) Tubular necrosis
b) Tubular obstruction
c) Tubular atrophy
d) Tubular dysplasia

User Ifeoma
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1 Answer

3 votes

Final answer:

The symptoms described indicate the student is dealing with tubular necrosis, a type of kidney dysfunction resulting from damage to the tubular cells that leads to impaired water and electrolyte regulation. so, option d is the correct answer.

Step-by-step explanation:

The type of tubular dysfunction described by the student - characterized by a potential toxic or hypoxic insult, decreased excretion/reabsorption ability, no response to antidiuretic hormone (ADH) and aldosterone, water and electrolyte imbalance, acidosis, and glycosuria - suggests the patient is experiencing tubular necrosis. Acute tubular necrosis is a renal disorder where the tubular cells of the kidneys are damaged, which can be due to ischemia or toxic injury.

Such damage impairs the kidney's ability to regulate water and electrolyte balance, does not respond well to hormonal signals like ADH and aldosterone that typically help regulate kidney function, and may result in the clinical features listed such as water and electrolyte imbalance, acidosis, and glycosuria. Normally, the kidneys play a crucial role in reabsorbing electrolytes like sodium and glucose, but with tubular necrosis, this function is disrupted, leading to the associated symptoms.

User Chris Ferdinandi
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