81.2k views
3 votes
What disease is characterized by elevated GGT & ALT > AST?

a. Hemochromatosis
b. Cirrhosis
c. Primary biliary cirrhosis
d. Gilbert's syndrome

User Fabasoad
by
7.2k points

1 Answer

3 votes

Final answer:

Cirrhosis is the disease characterized by elevated GGT and ALT levels, with ALT > AST.

Step-by-step explanation:

The disease characterized by elevated GGT (gamma-glutamyltransferase) and ALT (alanine aminotransferase) levels, with ALT > AST (aspartate aminotransferase), is cirrhosis (option b).

In cirrhosis, there is chronic liver failure, which can be caused by various factors such as excessive alcohol intake, hepatitis B or C, autoimmune diseases, hereditary conditions, and metabolic causes like iron or copper overload or non-alcoholic fatty liver disease.

GGT is a liver enzyme that can be elevated with liver dysfunction, and ALT is a liver enzyme that is more specific to liver damage. In cirrhosis, ALT levels are typically higher than AST levels.

User Invisible Squirrel
by
7.6k points