Question

What is happening in Neonatal physiologic jaundice that can cause conjugation failure leading to hepatic jaundice or pre-hepatic jaundice?

a) Immature liver enzyme activity
b) Overproduction of bilirubin
c) Impaired bilirubin transport
d) Excessive alcohol consumption

Answer 1

Neonatal physiologic jaundice can lead to hepatic or pre-hepatic jaundice due to immature liver enzyme activity.

Step-by-step explanation:

In neonatal physiologic jaundice, conjugation failure can lead to hepatic jaundice or pre-hepatic jaundice due to immature liver enzyme activity. In this condition, the liver's ability to effectively process and excrete bilirubin is not fully developed. As a result, unconjugated bilirubin accumulates in the blood, causing jaundice.