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What are the sources of error when measuring creatinine (7)?

a) Instrumentation, Technologist experience
b) Diet, Age
c) Hemolysis, Bilirubinemia
d) Hydration status, Medication

1 Answer

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Final answer:

Measurement errors when assessing creatinine levels may arise from technical factors such as the precision of instruments, the expertise of the medical staff, interference from substances in the blood such as hemolysis or bilirubinemia, and physiological variables including diet, age, hydration, and medications.

Step-by-step explanation:

The sources of error when measuring creatinine can include factors such as instrumentation accuracy, the experience of the technologist performing the test, the presence of hemolysis or bilirubinemia which can interfere with the creatinine measurement, patient's diet and age, their hydration status, as well as the influence of certain medications. It's crucial to consider these variables when interpreting creatinine levels, as they can impact the accuracy of the glomerular filtration rate (GFR) measurement, which is needed for assessing kidney function using standard procedures like the creatinine clearance test.

The hydration status of the patient can affect creatinine levels. Dehydration can lead to higher creatinine levels, while excess fluid intake can lower levels. The mentioned factors are important for medics and scientists as creatinine levels play a significant role in diagnosing and monitoring kidney health and function.

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