Final answer:
Diffuse Large B-cell Lymphoma (DLBCL) is a common and aggressive B-cell non-Hodgkin Lymphoma with symptoms including fatigue and swollen lymph nodes.
Step-by-step explanation:
Diffuse Large B-cell Lymphoma (DLBCL) is the most common type of non-Hodgkin Lymphoma (NHL) affecting B cells, appearing large under microscopy. It presents with symptoms like fatigue, swollen lymph nodes, and weight loss, accompanied by fever and night sweats. Despite being a fast-growing lymphoma, early detection and treatment lead to a cure rate of about 70%. DLBCL can occur in any age group but is more common in older adults, with variations in subtypes and presentation depending on different factors, including immune status and viral infections like Epstein-Barr virus (EBV).
DLBCL is an aggressive cancer, which if not treated, can be fatal. However, advancements in medical therapy, particularly using immunotherapy in conjunction with chemotherapy and radiation, have improved patient outcomes. Diagnosis involves biopsy, staging through computed tomography (CT) scans, and other cytologic evaluations. Treatments like rituximab have shown efficacy in drastically improving survival rates for DLBCL patients.