Final answer:
A saline nasal spray with a 0.65% concentration typically requires 1-2 sprays in each nostril.
Step-by-step explanation:
A saline nasal spray with a 0.65% concentration means that 0.65 grams of sodium chloride are contained in 100 milliliters of solution. Since most nasal spray bottles are 15-30 milliliters, we can calculate the number of sprays required using this information. For each nostril, 1-2 sprays are generally recommended, so for a 15-30 milliliter bottle, the suggested dose would be A) 1-2 sprays in each nostril.