Question

Reduction in LIS1 or dynein expression is likely to increase:

a) Synaptic plasticity
b) Neurotransmitter release
c) Neuronal migration abnormalities
d) Axonal myelination

Answer 1

Reduction in expression of LIS1 or dynein is likely to increase neuronal migration abnormalities.

Step-by-step explanation:

Neuronal migration abnormalities refer to disorders or conditions in which neurons (nerve cells) fail to migrate to their appropriate locations in the brain during fetal development. Neuronal migration is a crucial process in the formation of the nervous system, and disruptions in this process can lead to various neurological disorders.

Reduction in LIS1 or dynein expression is likely to increase neuronal migration abnormalities. LIS1 and dynein play important roles in neuronal migration, and a decrease in their expression can lead to abnormal neuronal migration, which can result in structural and functional defects in the brain.