Final answer:
The most important instruction for a patient on phenytoin is to take the medication consistently at the same time every day to maintain stable blood levels and prevent seizures.
Step-by-step explanation:
The instruction most important to prevent precipitation of seizures in a patient being treated with phenytoin is to take phenytoin consistently at the same time every day. Phenytoin is an antiepileptic drug, and maintaining a consistent blood level of the medication is crucial for seizure control. Improper dosing or erratic administration can lead to subtherapeutic levels and potential seizure breakthrough. It is particularly important not to skip doses when feeling well or to double the dose if one is missed, as these practices can disrupt drug levels and increase the risk of seizures. Additionally, phenytoin should not be taken with grapefruit juice, as it can interfere with the metabolism of the drug, potentially leading to toxicity.