Final Answer:
The over-the-counter weight loss medication Orlistat inhibits lipase enzyme
Therefore, correct option is a) Lipase.
Step-by-step explanation:
Orlistat, an over-the-counter weight loss medication, inhibits the enzyme lipase (a). Lipase is an enzyme responsible for breaking down dietary fats into smaller molecules that can be absorbed by the body. By inhibiting lipase activity, Orlistat reduces the absorption of dietary fats, leading to decreased caloric intake and facilitating weight loss.
Orlistat's mechanism of action occurs in the gastrointestinal tract, specifically in the stomach and small intestine. The drug forms a covalent bond with the active site of pancreatic and gastric lipases, preventing them from breaking down triglycerides into absorbable free fatty acids. Consequently, these undigested fats are excreted, resulting in a reduction of overall calorie absorption.
Therefore, correct option is a) Lipase.