Final answer:
The primary compliance issue with seizure medications is side effects, which can be significant and deter patients from adhering to their treatment regimen. In terms of litigation, the degree to which a search and seizure is deemed reasonable is often a central issue in legal challenges.
Step-by-step explanation:
The biggest issue of compliance with seizure meds is b) Side effects. While factors like financial constraints and the taste of medications can play a role in medication adherence, side effects are often the primary concern because they directly affect a patient's quality of life and can make it unpleasant or harmful to continue taking the medication. Fear of needles is generally not relevant for seizure medications, as they are usually administered orally, although in some cases, injectable forms may be used.
Much of the litigation surrounding issues of search and seizure concerns b) the degree to which the search and seizure is reasonable. This is central to debates and legal challenges in many cases involving the Fourth Amendment of the U.S. Constitution, which protects individuals against unreasonable searches and seizures and requires any warrant to be judicially sanctioned and supported by probable cause.