Question

MS-AFP and Estriol levels are LOW, inhibin-A and hCG are HIGH?

a) Neural tube defects
b) Down syndrome
c) Trisomy 18
d) Turner syndrome

Answer 1

The combination of low MS-AFP and Estriol levels, and high inhibin-A and hCG levels indicate Down syndrome (47 XXY), which is characterized by an extra copy of chromosome 21 in the cells.

Step-by-step explanation:

The combination of low MS-AFP and Estriol levels, and high inhibin-A and hCG levels is consistent with Down syndrome (47 XXY). Down syndrome is caused by an extra copy of chromosome 21 in the cells, which leads to developmental and intellectual disabilities. The presence of high inhibin-A and hCG levels can be attributed to the abnormal genetic makeup in Down syndrome.