Final answer:
The best response by the nurse would be to inform the parents that holding the premature baby frequently is essential for their development.
Step-by-step explanation:
The best response by the nurse is 'It's essential for the baby's development to be held frequently.'
Physical contact and holding are important for the development of preterm infants. It helps in forming a strong bond between the parents and the baby. Holding also provides warmth, comfort, and support to the baby, which can have positive effects on their growth and well-being. It is essential for the parents to understand the importance of holding their infant for their overall development.