Final answer:
Mini-column abnormalities can lead to impaired social communication in individuals with Autism Spectrum Disorder (ASD).
Step-by-step explanation:
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interaction and communication abilities. One of the characteristics of ASD is impaired social skills, which includes difficulty in making and maintaining eye contact and understanding social cues. Therefore, mini-column abnormalities in individuals with ASD may lead to impaired social communication (option c).