Question

Is a nitrate-free interval needed while a patient is on hydralazine + nitrate therapy?

a) Yes, a nitrate-free interval is required.
b) No, a nitrate-free interval is not needed.
c) It depends on the patient's age.
d) Only if the patient experiences adverse effects.

Answer 1

A nitrate-free interval is usually not needed while a patient is on hydralazine + nitrate therapy.

Step-by-step explanation:

When a patient is on hydralazine + nitrate therapy, a nitrate-free interval is usually not needed. Nitrate-free intervals are typically required for patients on long-acting nitrates to prevent tolerance from developing. However, hydralazine functions as a direct vasodilator and does not lead to the same tolerance issues as nitrates. Therefore, a nitrate-free interval is generally not necessary for patients on hydralazine + nitrate therapy.