Final answer:
The target dose of enalapril for the treatment of heart failure is 10 mg twice daily. It's important to start at a lower dose and titrate upwards to the target dose, monitoring the patient's response and adjusting as needed.
Step-by-step explanation:
The target dose of enalapril in heart failure is option B) 10 mg twice daily. Enalapril is an ACE inhibitor used to treat high blood pressure, symptomatic heart failure, and to prevent symptomatic heart failure in patients with left ventricular dysfunction. The goal in heart failure treatment is to reach the target dose that has been shown to be effective in clinical trials, while also taking into consideration the patient's tolerability and response to medication.
The typical starting dose is lower, usually at 2.5 mg to 5 mg twice daily, to minimize the risk of side effects, particularly in patients who are at higher risk, like those with renal impairment or those who are sodium depleted. The dose is then gradually increased to the target dose, which is 10 mg twice daily, under careful medical supervision. It is essential that dose adjustments be made based on the patient's clinical response and tolerability, with regular monitoring of blood pressure, renal function, and potassium levels.