Final answer:
A GBS culture is taken during the third trimester of pregnancy, between 35 and 37 weeks, to prevent the potential transfer of bacteria to the infant during childbirth.
Step-by-step explanation:
A Group B Streptococcus (GBS) culture is typically taken during the third trimester of pregnancy, specifically between 35 and 37 weeks gestation. This is a critical time for GBS screening because, during childbirth, the bacteria can be transferred from the mother's vagina to the infant, potentially resulting in early onset disease. Answer C) Third trimester is correct. Antibiotics given to the mother during labor can significantly reduce the incidence of early onset neonatal meningitis caused by S. agalactiae, which underscores the importance of timely GBS culture.