Question

What is important to know about Propylthiouracil/PTU?

a) Indications and contraindications
b) Monitoring requirements and expected outcomes
c) Patient education and action in case of adverse effects
d) Drug interactions and administration timing

Answer 1

Propylthiouracil/PTU is indicated for the treatment of hyperthyroidism and requires regular monitoring. Patients should be educated about potential adverse effects and drug interactions.

Step-by-step explanation:

Important information about Propylthiouracil/PTU

1. Indications and contraindications: PTU is indicated for the treatment of hyperthyroidism, specifically Graves' disease. It is contraindicated in patients with liver disease or hypersensitivity to PTU.
2. Monitoring requirements and expected outcomes: PTU treatment requires regular monitoring of thyroid function, liver function, and complete blood count. The expected outcome is to achieve normal thyroid function and resolution of hyperthyroidism symptoms.
3. Patient education and action in case of adverse effects: Patients should be educated about the potential adverse effects of PTU, such as rash, liver toxicity, and agranulocytosis. They should be advised to seek immediate medical attention if they experience any severe adverse effects.
4. Drug interactions and administration timing: PTU can interact with other drugs, particularly those that affect liver enzymes. It should be taken with food to enhance absorption.