Final answer:
Liver function tests are essential to review before starting pharmacotherapy in a client with tuberculosis associated with HIV, to ensure the liver can properly metabolize the medications and to avoid potential hepatotoxicity.
Step-by-step explanation:
Before starting antitubercular pharmacotherapy in a client diagnosed with tuberculosis associated with human immunodeficiency virus (HIV) infection, it is crucial to review Liver function tests. These tests include levels of alkaline phosphatase, alanine aminotransferase (ALT), aspartate aminotransferase (AST), direct bilirubin, total bilirubin, serum albumin, serum total protein, and calculated globulin, which are necessary for assessing the liver’s capability to metabolize the anti-TB medications. As tuberculosis medications can be hepatotoxic, ensuring that the liver is functioning well is vital for safe treatment administration and avoiding further complications.