Question

When taking medications, one concern for someone who has kidney disease would be

A) Drug accumulation leading to toxicity
B) Increased drug metabolism
C) Reduced drug efficacy
D) Allergic reactions

Answer 1

Option A, Drug accumulation leading to toxicity, is a concern for individuals with kidney disease as impaired kidney function can lead to a buildup of drugs to toxic levels in the body.

Step-by-step explanation:

When taking medications, a concern for someone with kidney disease would be Drug accumulation leading to toxicity (Option A). The kidneys are crucial for filtering waste products from the blood and regulating bodily fluids. When kidney function is impaired, as in kidney disease, the elimination process for many drugs is compromised. This can lead to a buildup of drugs in the body to toxic levels because the kidneys are not efficient at excreting them. Drugs are often metabolized and then excreted by the kidneys, and if kidney function is reduced, drug accumulation can occur and increase the risk of toxicity. This problem highlights the importance of carefully monitoring and adjusting medication dosages in patients with kidney disease.