Final answer:
Local anesthesia is the creation of loss of sensation in a specific area without loss of consciousness.
Step-by-step explanation:
The creation of the loss of sensation in a circumscribed area, without loss of consciousness, is best defined as local anesthesia. Local anesthetics are drugs that block nerve conduction and cause a reversible loss of sensation for a limited region of the body without affecting consciousness. These drugs act on nerve tissue and prevent the initiation and transmission of sensory impulses.