Question

Event must be reported if fractionated dose differs from the prescribed dose, for a single fraction, by _____% Or more

a) 5%
b) 10%
c) 15%
d) 20%

Answer 1

The fractionated dose must be reported when it differs from the prescribed dose by 5% or more. This is crucial for medical safety protocols. 'Effective dose - 50%' refers to the dose causing a significant response in 50% of subjects.

Step-by-step explanation:

The question pertains to standards of practice in medicine, specifically regarding the administration of fractionated doses in treatments such as radiotherapy. When the fractionated dose delivered differs from the prescribed dose by 5% or more, this must be reported. This falls under medical error reporting guidelines, which are crucial for patient safety and treatment efficacy.

To further clarify, let's look at the possible scenarios regarding percentage differences:

• When a fractionated dose differs from the prescribed dose by at least 20 percent, it indicates a significant dosing error and underscores the need for immediate corrective action.
• If the difference is exactly 20 percent, it is a clear deviation from the prescribed treatment that must be reported.
• Differences less than 20 percent are still considered errors if they reach or exceed the 5 percent threshold.

Additionally, understanding terms like "Effective dose - 50%" is important in this context. It describes the dose that results in a significant response in 50% of subjects (Answer D), not necessarily mortality or survival rates.