Final answer:
The physician is most likely to prescribe selective serotonin reuptake inhibitors (SSRIs) for a client with major depression who experiences excessive sleep, loss of interest in activities, and weight loss.
Step-by-step explanation:
The physician is most likely to prescribe selective serotonin reuptake inhibitors (SSRIs) for a client with major depression who sleeps excessively, shows no interest in previously enjoyed activities, and has experienced weight loss. SSRIs are a class of antidepressant medications that work by blocking the reuptake of serotonin, increasing its concentration in the synaptic cleft. This helps alleviate the symptoms of depression and improve mood.