Final answer:
When administering surfactant by direct instillation, the RT should anticipate respiratory alkalosis due to hyperventilation caused by increased ventilation.
Step-by-step explanation:
When administering exogenous surfactant by direct instillation, the respiratory therapist (RT) should anticipate the adverse event of respiratory alkalosis. Respiratory alkalosis occurs when there is an excess of carbon dioxide elimination, leading to a decrease in carbon dioxide levels in the blood. This can occur as a result of the instillation of surfactant, which can stimulate breathing and cause hyperventilation. The increased ventilation can then lead to respiratory alkalosis.