Final answer:
The most effective statement to indicate understanding of the warnings associated with ibuprofen is that the medication can cause peptic ulcerations and life-threatening gastrointestinal bleeding.
Step-by-step explanation:
The statement that indicates the education about the use of ibuprofen (Motrin) has been most effective is option D: "This medication can cause peptic ulcerations and life-threatening gastrointestinal bleeding." This statement demonstrates an understanding of the warnings and precautions associated with ibuprofen, emphasizing the potential risk of peptic ulcerations and gastrointestinal bleeding that can occur when taking the medication.