Question

Infants are at risk for drug toxicity due to which of the following? (select all that apply)

A. decreased liver enzymes
B. reduced kidney perfusion
C. increased stomach acid
D. reduced percentage of body water
E. reduced liver perfusion

Answer 1

Infants are at risk for drug toxicity due to decreased liver enzymes, reduced kidney perfusion, and reduced percentage of body water.

Step-by-step explanation:

Infants are at risk for drug toxicity due to the following factors:

1. Decreased liver enzymes: Infants have lower levels of liver enzymes, which play a crucial role in metabolizing drugs. This can lead to a slower clearance of drugs from the body and an increased risk of toxicity.
2. Reduced kidney perfusion: The kidneys are responsible for filtering drugs and removing them from the body. In infants, reduced kidney perfusion can affect the elimination of drugs, increasing the risk of toxicity.
3. Reduced percentage of body water: Infants have a higher proportion of body water compared to adults. This means that the concentration of drugs in their body can be higher, potentially leading to toxicity.