Final answer:
The principle that emphasizes the promotion of the patient's well-being and best interests in healthcare is Beneficence.
Step-by-step explanation:
In the context of ethical principles in healthcare, the principle that emphasizes the promotion of the well-being and best interests of the patient is Beneficence. The Principle of Beneficence states that healthcare professionals should act in ways that benefit patients and contribute to their welfare. This principle is distinguished from Non-Maleficence, which focuses on the obligation to do no harm, and Respect for Autonomy, which deals with respecting the decision-making capacities of autonomous persons. While Fidelity refers to loyalty and commitment to the patient, it is Beneficence that is directly concerned with the promotion of positive well-being.