Final answer:
The statement is false; PCA typically involves the intravenous or subcutaneous administration of opioids, not oral medications, to manage severe postoperative pain.
Step-by-step explanation:
The statement that Patient-controlled analgesia (PCA) can be used with oral analgesic agents to treat mild to moderate postoperative pain is false. PCA is typically associated with the administration of opioids through intravenous or subcutaneous routes, not oral administration. Drugs such as aspirin and other non-opioid medications like acetaminophen may indeed be used to control mild to moderate pain, but they are not typically administered through PCA systems. PCA allows patients to self-administer controlled quantities of analgesics, often opioids like morphine or oxycodone, to manage severe postoperative pain. These medications are effective against pain of varying intensities and are provided directly via an IV, bypassing the digestive system for a more immediate effect compared to oral agents.