Final answer:
Enzymes speed up reactions by lowering activation energy, while the overall energy released and the products remain the same.
Step-by-step explanation:
When comparing a reaction with and without an enzyme, there are several differences. One of the differences is that the reaction proceeds at a faster rate with the enzyme, as the enzyme lowers the activation energy required for the reaction to start. Another difference is that the reaction with the enzyme releases the same amount of energy overall, but it requires less energy input to begin. Lastly, the reaction with the enzyme produces the same products as the reaction without the enzyme.