Final answer:
Disorders of glycogen metabolism such as diabetes mellitus and hyperinsulinism can lead to hypoglycemia.
Step-by-step explanation:
Disorders of glycogen metabolism are characterized by varying or persistent hypoglycemia (low blood sugar).
One of these disorders is diabetes mellitus, which is a dysfunction of insulin production and secretion, as well as the target cells' responsiveness to insulin. Another disorder is hyperinsulinism, which is characterized by excessive production of insulin, mainly due to tumors of the β-cells in the pancreas.
Additionally, glycogen storage diseases can also lead to hypoglycemia due to defective enzymes of glycogen metabolism in the liver.