Final answer:
The most common disease involving glycogen is type 2 diabetes, which leads to high blood glucose levels due to insulin resistance and impaired insulin secretion.
Step-by-step explanation:
The most common disease involving glycogen is type 2 diabetes. Type 2 diabetes is characterized by insulin resistance and impaired insulin secretion, resulting in high blood glucose levels. This condition is a result of both genetic and environmental factors, and management includes lifestyle changes and medication, with the aim of increasing insulin sensitivity and lowering blood glucose levels. Glycogen storage diseases, on the other hand, involve defective enzymes of glycogen metabolism resulting in the build-up of abnormal glycogen and are often associated with hypoglycemia. Type 1 diabetes, not directly tied to glycogen storage but important in the context of diabetes, is an autoimmune disorder where the beta cells of the pancreas are destroyed, leading to a lack of insulin production and a rise in blood glucose levels.