Final answer:
A characteristic morphological RBC feature in G6PD deficiency are Heinz bodies. These are inclusions that represent denatured hemoglobin and make RBCs susceptible to hemolysis under oxidative stress.
Step-by-step explanation:
A characteristic morphological RBC feature in G6PD deficiency are Heinz bodies. These are inclusions within the red blood cells that represent denatured hemoglobin precipitates, visible with special staining. Such RBCs are more prone to hemolysis, especially under oxidative stress.
G6PD deficiency is considerable in males due to its X-linked pattern of inheritance, but female carriers can also be affected. These individuals with G6PD deficiency may develop hemolytic anemia upon exposure to certain triggers like infections or foods such as fava beans due to the lack of protection against oxidative damage.
It is essential to recognize that different morphological features are associated with various RBC disorders. For example, in sickle cell disease, which is also a genetic disorder, erythrocytes assume a crescent or 'sickle' shape, unlike the Heinz body inclusion seen in G6PD deficiency.