Final answer:
The U.S. Indian policy in the early years of the nation was indeed driven by the motive to acquire land, evidenced by treaties and legislative acts such as the Indian Removal Act of 1830.
Step-by-step explanation:
The statement that acquisition of land was the most important motivating factor in the formulation of early U.S. Indian policy is true. The early policies of the United States towards Native American tribes were heavily influenced by the desire to expand and control more territory. This push for westward expansion meant that treaties were often made with tribes to acquire their land, and in many cases, force was used to remove Native Americans from their ancestral homes. This policy of land acquisition was formalized through various acts and legal decisions, such as the Indian Removal Act of 1830, which led to events like the Trail of Tears.