Final answer:
The area in question was known as the Northwest Territory, which was established and organized by the Northwest Ordinance of 1787.
Step-by-step explanation:
The land West of the Appalachian Mountains to the Mississippi River and North of the Ohio River was known as the Northwest Territory. This area was organized into an incorporated territory following the passage of the Northwest Ordinance in 1787. The ordinance established the method by which new states would be admitted to the Union, prohibited slavery in the new territories, and laid out a grid system for land sales which remains part of the American landscape to this day. It included what are now the states of Illinois, Indiana, Michigan, Ohio, Minnesota, and Wisconsin.