Final answer:
Ms. McCalla will mainly use her skeletal and muscular systems to run a mile, as they allow for movement and support. The skeletal system includes bones and joints, while the muscular system involves muscle contraction.
Step-by-step explanation:
When Ms. McCalla wants to run a mile, she will be primarily using her skeletal system and muscular system. The skeletal system includes bones and joints like the knee, which allow the legs to move. The skeletal system's bones provide support and protection for the body's internal organs. On the other hand, the muscular system is responsible for the contraction of muscles which in turn pull on the bones, facilitating movements necessary for running. Both systems work together to enable locomotion and are essential for activities such as standing, walking, and running.
Running also involves the circulatory system and the respiratory system to a considerable extent, which supply the necessary oxygen and nutrients to the muscles and remove waste products. However, the specific systems mentioned in the multiple-choice options provided (A. Skeletal system and muscular system B. Muscular system and digestive system C. Endocrine system and reproductive system D. Cardiovascular system and urinary system) clearly indicate that the best answer within the given context would be A. Skeletal system and muscular system, as they provide the direct means for movement.