Final answer:
The Harlem Renaissance most significantly impacted culture and the arts, as it fostered a flowering of African American culture and integrated it into the broader American cultural identity.
Step-by-step explanation:
The area of American life most affected by the events of the Harlem Renaissance was culture and the arts. This period saw a flourishing of African American culture, particularly in New York City's Harlem neighborhood. Artists, writers, and musicians influenced by the movement contributed to a significant change in American culture, blending the African American experience into a broader national identity.
The literature, music, and fashion developed during the Harlem Renaissance not only fostered racial pride but also became integral to the American cultural landscape.