Question

Sickle cell disease and cystic fibrosis are among the genetic diseases that are life threatening. Can a karyotype be used to analyze the presence of these diseases in a person?

a. No because the 2 diseases are only found in plant cells that are not visible using karyotypes.
b. No because the 2 diseases are caused by point mutations that are not visible using karyotypes.
c. Yes because the 2 diseases are types of aneuploidy that are visible using karyotypes.
d. Yes because the 2 diseases are the result of crossing over that can be visible using karyotypes.

Answer 1

No, a karyotype cannot detect sickle cell disease or cystic fibrosis because they are caused by point mutations, which are too small to be visible on a karyotype.Hence, the correct answer is option B.

Step-by-step explanation:

The answer is b. No because the 2 diseases are caused by point mutations that are not visible using karyotypes. Sickle cell anemia and cystic fibrosis are both autosomal recessive disorders that are the result of point mutations in specific genes. A karyotype is effective in identifying chromosomal abnormalities such as aneuploidy or large DNA deletions or insertions, but it cannot detect the small-scale point mutations that cause sickle cell disease or cystic fibrosis. Instead, these diseases can be analyzed through molecular genetic tests that can identify the specific mutations in the DNA sequence.